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Volufuline & Poly-L-Lactic PLLA Active Ingredients

Volufuline & Poly-L-Lactic PLLA Active Ingredients

Posted by kelly ozmon on 06-24-2024

We absolutely love our heaven hitters and today I am going to explain the difference between PLLA, Poly L Lactic Acid & Volufiline.

Let's start with Volufiline, it is a patented cosmetic ingredient that is extracted from the roots of the Asian plant Anemarrhena asphodeloides and is used to add volume and elasticity to the skin. It is made of Sarsasapogenin, which is an adipocyte growth factor stimulator that helps fat cells grow faster. Sarsasapogenin is a phytosterol extracted from the roots of the Chinese medical herb Anemarrhena Asphodeloides, also known as Zhimu (Rhizoma Anemarrhenae). It's used in cosmetics to improve skin by Maintaining skin fat cells: it Helps reduce the loss of skin volume that occurs with age by maintaining adipocytes or more commonly known as skin fat cells. These fat pads, located below the skin's surface, provide volume, facial contours, and fullness. Plumping and smoothing skin and Can improve skin elasticity and reduce the appearance of wrinkles. It can enlarge subcutaneous adipose tissue and promote lipid synthesis. Essentially an epidermis Growth factor ingredient in many high-end skincare products that can help rejuvenate the skin. In this case Volufiline is extracted from the lilly plant, Anemarhena Asphodeloides. When applied topically, growth factors can communicate with cells to stimulate collagen and elastin production, which can improve skin texture and firmness. They can also help strengthen the skin barrier, repair and rejuvenate skin, and address concerns like scarring, acne, and hyperpigmentation. Volufiline works by stimulating adipocyte differentiation and proliferation, which leads to an increase in lipid storage and adipocyte volume in fatty tissue. This creates a cosmetic lipofilling-like effect that plumps the skin.

The effects of topical PLLA appear gradually over a few months, producing natural results. Volufiline – an extract from the roots of Asian Botanical Anemarrhena Asphodeloides, in an oil-soluble excipient. It promotes body volume by a cosmetic lipofilling-like effect. 

Our Stop Aging Peptide EssenceStop Aging Peptide Cream contain high levels of Volulfine 7 and additional peptides.


Poly-L-Lactic Acid, also known as PLLA, is a biodegradable, biocompatible polymer derived from lactic acid. PLLA can have a variety of molecular weights, similar to Hyaluronic Acid. Due to its biocompatibility, this compound can completely dissolve in the human body, making it highly versatile in modern medicine. In so many words, your body’s immune system will not attack it. As a result, you can find this substance in dissolvable sutures, pins, plates, screws, and other surgical applications. While it has over 30 years of history in clinical usage, PLLA has only found it’s place in aesthetics within the last ten to twenty years.

PLLA was first approved for soft tissue augmentation in 1999 to help correct cosmetic “blemishes/imperfections” like wrinkles and scars. It wasn’t until 2004 that the FDA cleared it for use in the US. It has since been used in procedures all around the country under the brand name Sculptra. Similar to other dermal fillers, Sculptra injections fill in hollow, sunken areas of the face to achieve a more youthful appearance. In the right conditions, these PLLA injections even boost your skin’s ability to produce collagen.

While fillers provide impressive results, they’re not for everyone. If you’re looking for a topical solution that provides similar benefits, you’re in luck! As it turns out, PLLA can plump and smooth the look of skin without the need for any injections. While there are scant clinical studies on the topical usage of Poly-L-Lactic Acid, it’s general safety and biocompatibility still stand. Anecdotally, I have seen great results, both personally and with clients, from products containing PLLA.


It’s got “Lactic Acid” in the name, so it’s similar to Lactic Acid, right? As with many chemical compounds, the whole behaves different than it’s parts. As I mentioned PLLA is a polymer, essentially a repeating chain of molecules. Lactic Acid is an alpha hydroxy acid (AHA) and functions as a chemical exfoliant in skincare. They are both very useful for promoting healthy aging of skin, but serve distinct purposes.


Besides the obvious confidence boost, consistent use of PLLA comes with a number of lasting benefits. In the short term, this ingredient smooths and plumps the skin, giving it a more vibrant and youthful appearance. With continued use, the increase in collagen production will slow cellular damage altogether and lead to improved skin elasticity and less defined wrinkles.

Order our High-Performance Collagen Gel


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