Experience the pinnacle of regenerative skin science at Jolie Day Spa. Our NeoGenesis® Stem Cell Exosome Facial with Microneedling is a medical-grade, highly restorative treatment designed to reverse structural aging and skin damage at a cellular level.

By pairing precision automated microneedling with advanced biotechnology, we create temporary microscopic channels in the skin. These channels act as direct pathways, delivering millions of bio-identical stem cell growth factors, exosomes, and targeted nutrients directly to the deeper dermal layers where true transformation happens.

The Advanced Product Technology

This clinical facial features a dual-phase delivery of patented NeoGenesis formulations:

• Phase 1: 70% Patented S²RM® Exosome Technology

  During the microneedling process, our Master Esthetician utilizes NeoGenesis Recovery Serum as a biological glide. Containing a 70% concentration of natural, adult stem cell-released molecules (exosomes), this formula infuses the tissue with the exact chemical signals the body uses to heal itself, triggering rapid collagen production and erasing inflammation.

• Phase 2: Skin Restore Vitamin A (HPR)

  The treatment concludes with NeoGenesis Skin Restore Serum. Powered by Hydroxypinacolone Retinoate (HPR)—a next-generation retinoid—it binds directly to your skin’s cellular receptors. It accelerates cell turnover and targets pigment clusters without causing the redness, peeling, or barrier damage associated with traditional retinol.

Key Clinical Benefits

• Deep Wrinkle & Line Remodeling: The mechanical action of microneedling breaks down old skin structures while the 70% exosome blend sparks a 41.2% improvement in overall skin texture, plumping deep lines and firming the jawline.

• Hyperpigmentation & Melasma Eradication: Micro-channels shatter dense melanin clusters. Simultaneously, the N-acetyl-D-glucosamine and protective carotenoids in the Skin Restore Serum work deep within the skin to fade sun-spots and age-spots safely.

• Unhealthy Skin Reset: This treatment strengthens a compromised skin barrier, refines coarse skin texture, minimizes stretched pores, and controls congestion by accelerating healthy cellular shedding.

• Ultra-Fast Healing & Minimal Downtime: Traditional microneedling can leave the skin red for up to 72 hours. Because our formula is packed with high-velocity anti-inflammatory molecules and heat shock proteins, post-treatment redness and swelling fade significantly faster—often within 24 hours.

What to Expect: Your Treatment Experience

1. In the Treatment Room

Your licensed Master Esthetician will deeply cleanse your skin and apply a medical-grade topical numbing cream to ensure total comfort. Using a sterile, automated device, the microneedling pen is gently guided across the target areas while being flooded with the 70% Exosome Recovery serum.

2. Immediate Post-Care (Days 1–3)

Your skin will look flushed, similar to a mild sunburn. Because your micro-channels remain highly absorbing for 72 hours, you will receive strict instructions to use only clean, non-reactive hydration and physical mineral SPF to protect the freshly treated barrier.

3. Continuous Restoration (Day 4+)

As the skin barrier closes, you will introduce the NeoGenesis Skin Restore Serum into your nightly home care routine to continuously fuel the cellular turnover initiated in the clinic.

4. The Transformation Timeline

An immediate "exosome glow" and smoother texture are visible within the first week. Deep structural changes—such as pigment fading and wrinkle softening—peak between 4 to 6 weeks as new collagen matrix fully matures.

Ready to Reveal Healthy, Vibrant Skin?

Book your advanced clinical treatment with our licensed Master Esthetician at our Murrieta location.

• Call to Schedule: 951-678-9080

• Location: Jolie Day Spa | 24885 Whitewood Rd, Suite 101, Murrieta, CA 92563

recommended treatment series (like 3 to 6 sessions) 

What to Expect: Your Treatment Experience

1. In the Treatment Room

Your licensed Master Esthetician will deeply cleanse your skin and apply a medical-grade topical numbing cream to ensure total comfort. Using a sterile, automated device, the microneedling pen is gently guided across the target areas while being flooded with the 70% Exosome Recovery serum.

2. Immediate Post-Care (Days 1–3)

Your skin will look flushed, similar to a mild sunburn. Because your micro-channels remain highly absorbing for 72 hours, you will receive strict instructions to use only clean, non-reactive hydration and physical mineral SPF to protect the freshly treated barrier.

3. Continuous Restoration (Day 4+)

As the skin barrier closes, you will introduce the NeoGenesis Skin Restore Serum into your nightly home care routine to continuously fuel the cellular turnover initiated in the clinic.

4. The Transformation Timeline

An immediate "exosome glow" and smoother texture are visible within the first week. Deep structural changes—such as pigment fading and wrinkle softening—peak between 4 to 6 weeks as new collagen matrix fully matures.

Ready to Reveal Healthy, Vibrant Skin?

• Faster Redness Reduction: A controlled clinical trial led by dermatologist Dr. Raja Sivamani demonstrated that erythema (skin redness) faded significantly faster on the facial side treated with NeoGenesis Recovery serum. [1]
• 91% Success Rate: In the same trial, 91% of participants experienced faster and superior visual improvements in overall skin quality.
• Scar and Texture Smoothing: Case studies from licensed estheticians highlight dramatic reductions in stubborn acne scars, refined pore sizes, and the softening of deep wrinkles.
• Hair and Scalp Regrowth: When paired with the NeoGenesis Hair Thickening Serum, microneedling or microchanneling has been shown to spark new follicle growth in stubborn areas like the temples within 4 to 5 months. 

• First 24 Hours Only: Gently cleanse and apply only NeoGenesis Recovery 3 to 4 times throughout the day to speed up structural repair.
• Days 2 to 7: Cleanse, apply Recovery serum, and layer with NeoGenesis Barrier Renewal Cream twice daily. Always finish with a physical mineral sunscreen during daytime hours.
• Day 8 and Beyond: Transition the Recovery serum exclusively to your evening skincare routine, followed by your regular moisturizer.